Chemistry:Pynazolam

From HandWiki
Short description: Chemical compound
Pynazolam
Pynazolam structure.png
Identifiers
CAS Number
PubChem CID
ChemSpider
Chemical and physical data
FormulaC16H12N6O2
Molar mass320.312 g·mol−1
3D model (JSmol)

Pynazolam is a triazolobenzodiazepine derivative first invented in the 1970s,[1] which has in more recent years been sold online as a designer drug. Anecdotal reports and in silico studies suggest it has relatively potent hypnotic and sedative effects. Pynazolam is a powerful serotonin releaser similar to nimetazepam[2] which increases hypnotic activity and euphoria. Anecdotal evidence has also suggested that it's subjective effects are similar to methaqualone[3] although unlike methaqualone, it cannot be smoked due to high melting-point.

Sadly only limited pharmacological data is available.[4]

See also

References

  1. Sternbach LH, Walser A, "Preparation of triazolo benzodiazepines.", US patent 3970664, issued 20 July 1976.
  2. Pranzatelli, Michael R. (1989). "Benzodiazepine-induced shaking behavior in the rat: Structure-activity and relation to serotonin and benzodiazepine receptors". Experimental Neurology 104 (3): 241–250. doi:10.1016/0014-4886(89)90036-8. 
  3. https://bluelight.org/xf/threads/flubromazolam-retrospective-6-years-with-the-knockout-night-nurse.892802/page-7
  4. "In silico studies on recreational drugs: 3D quantitative structure activity relationship prediction of classified and de novo designer benzodiazepines". Chemical Biology & Drug Design 101 (1): 40–51. January 2023. doi:10.1111/cbdd.14119. PMID 35838189.