Chemistry:Bivatuzumab mertansine

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Short description: Chemical compound
Bivatuzumab mertansine
Mertansine mab structure.svg
Monoclonal antibody
TypeWhole antibody
SourceHumanized (from mouse)
TargetCD44 v6
Clinical data
ATC code
  • none
Identifiers
ChemSpider
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Bivatuzumab mertansine is a combination of bivatuzumab, a humanized monoclonal antibody, and mertansine, a cytotoxic agent. It is designed for the treatment of squamous cell carcinoma.[1]

References

  1. "A phase I dose escalation study with anti-CD44v6 bivatuzumab mertansine in patients with incurable squamous cell carcinoma of the head and neck or esophagus". Clinical Cancer Research 12 (20 Pt 1): 6064–72. October 2006. doi:10.1158/1078-0432.CCR-06-0910. PMID 17062682.