Biology:GTF3A
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Transcription factor IIIA is a protein that in humans is encoded by the GTF3A gene.[1][2]
It was first purified and identified as the first mammalian gene-specific activator by Roeder in 1980,[3] and later characterized by Wolffe and Brown in 1988.
The TFIIIA in Xenopus was the first zinc finger protein discovered.[4]
References
- ↑ "Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA". Cytogenetics and Cell Genetics 70 (3–4): 235–8. Jul 1995. doi:10.1159/000134041. PMID 7789179.
- ↑ "Entrez Gene: GTF3A general transcription factor IIIA". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=2971.
- ↑ "Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes". Cell 19 (3): 717–28. Mar 1980. doi:10.1016/S0092-8674(80)80048-1. PMID 6153931.
- ↑ "The Arms Race Between KRAB-Zinc Finger Proteins and Endogenous Retroelements and Its Impact on Mammals". Annual Review of Genetics (Annual Reviews) 53 (1): 393–416. December 2019. doi:10.1146/annurev-genet-112618-043717. PMID 31518518.
Further reading
- "Specific interaction of a purified transcription factor with an internal control region of 5S RNA genes". Cell 19 (3): 717–28. Mar 1980. doi:10.1016/S0092-8674(80)80048-1. PMID 6153931.
- "Recognition sites for clathrin-associated proteins AP-2 and AP-3 on clathrin triskelia". The Journal of Biological Chemistry 267 (15): 10850–5. May 1992. doi:10.1016/S0021-9258(19)50096-5. PMID 1587861.
- "Purification of human transcription factor IIIA and its interaction with a chemically synthesized gene encoding human 5 S rRNA". The Journal of Biological Chemistry 264 (3): 1702–9. January 1989. doi:10.1016/S0021-9258(18)94243-2. PMID 2912980.
- "Cloning and expression analysis of a human cDNA homologous to Xenopus TFIIIA". Gene 159 (2): 215–8. July 1995. doi:10.1016/0378-1119(95)00145-V. PMID 7622052.
- "Purification and characterization of human transcription factor IIIA". The Journal of Biological Chemistry 269 (33): 20857–65. August 1994. doi:10.1016/S0021-9258(17)31901-4. PMID 8063702.
- "Amphibian transcription factor IIIA proteins contain a sequence element functionally equivalent to the nuclear export signal of human immunodeficiency virus type 1 Rev". Proceedings of the National Academy of Sciences of the United States of America 93 (7): 2936–40. April 1996. doi:10.1073/pnas.93.7.2936. PMID 8610146. Bibcode: 1996PNAS...93.2936F.
- "Human transcription factors IIIC2 , IIIC1 and a novel component IIIC0 fulfil different aspects of DNA binding to various pol III genes". Nucleic Acids Research 25 (12): 2440–7. June 1997. doi:10.1093/nar/25.12.2440. PMID 9171097.
- "Identification of a transcription factor IIIA-interacting protein". Nucleic Acids Research 28 (9): 1986–93. May 2000. doi:10.1093/nar/28.9.1986. PMID 10756201.
- "Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors". Molecular and Cellular Biology 21 (22): 7796–806. November 2001. doi:10.1128/MCB.21.22.7796-7806.2001. PMID 11604514.
- "cDNA cloning, DNA binding, and evolution of mammalian transcription factor IIIA". Gene 282 (1–2): 43–52. January 2002. doi:10.1016/S0378-1119(01)00796-X. PMID 11814676.
- "Assembly and isolation of intermediate steps of transcription complexes formed on the human 5S rRNA gene". Nucleic Acids Research 31 (9): 2408–16. May 2003. doi:10.1093/nar/gkg345. PMID 12711686.
- "Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis". Clinical Cancer Research 10 (22): 7621–8. November 2004. doi:10.1158/1078-0432.CCR-04-1061. PMID 15569994.
- "Clathrin adaptor AP2 regulates thrombin receptor constitutive internalization and endothelial cell resensitization". Molecular and Cellular Biology 26 (8): 3231–42. April 2006. doi:10.1128/MCB.26.8.3231-3242.2006. PMID 16581796.
- "Transient suppression of PPARgamma directed ES cells into an osteoblastic lineage". FEBS Letters 580 (17): 4121–5. July 2006. doi:10.1016/j.febslet.2006.06.057. PMID 16828750.
- "Loss of AP-2alpha results in deregulation of E-cadherin and MMP-9 and an increase in tumorigenicity of colon cancer cells in vivo". Oncogene 26 (28): 4049–58. June 2007. doi:10.1038/sj.onc.1210193. PMID 17224907.
External links
- GTF3A+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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