Biology:(S)-corytuberine synthase

From HandWiki
Short description: Enzyme
(S)-corytuberine synthase
Identifiers
OrganismCoptis japonica
SymbolCYP80G2
Alt. symbolsCorytuberine synthase
UniProtA8CDR5
Other data
EC number1.14.19.51

(S)-corytuberine synthase is a cytochrome P450 enzyme purified from the plant Coptis japonica (Japanese goldthread),[1] with EC number EC 1.14.19.51 and CYP Symbol CYP80G2 (Cytochrome P450, family 80, member G2), and catalyses an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis.[2]

References

  1. "Molecular cloning and characterization of CYP80G2, a cytochrome P450 that catalyzes an intramolecular C-C phenol coupling of (S)-reticuline in magnoflorine biosynthesis, from cultured Coptis japonica cells". The Journal of Biological Chemistry 283 (14): 8810–21. April 2008. doi:10.1074/jbc.M705082200. PMID 18230623. 
  2. "Coregulation of Biosynthetic Genes and Transcription Factors for Aporphine-Type Alkaloid Production in Wounded Lotus Provides Insight into the Biosynthetic Pathway of Nuciferine". ACS Omega 3 (8): 8794–8802. August 2018. doi:10.1021/acsomega.8b00827. PMID 31459012.