Medicine:Provascular anticancer therapy
From HandWiki
| Provascular anticancer therapy | |
|---|---|
| Specialty | oncology |
Provascular anticancer therapy is a strategy that exploits the differential reactivity of mature tumor blood vessels to increase the efficacy of conventional anticancer treatments (such as radiotherapy and chemotherapy).[1] Based on the identification of an altered regulation of vascular reactivity in tumors, the provascular approach aims at selectively inducing a transient dilation of functional tumor microvessels, leading to increased tumor perfusion, increased drug delivery and increased tumor oxygenation and radiosensitivity.
References
- ↑ Feron O (October 2004). "Targeting the tumor vascular compartment to improve conventional cancer therapy". Trends Pharmacol. Sci. 25 (10): 536–42. doi:10.1016/j.tips.2004.08.008. PMID 15380938.
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