Chemistry:TTFB (chemical)
From HandWiki
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3D model (JSmol)
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PubChem CID
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| Properties | |
| C8HCl4F3N2 | |
| Molar mass | 323.91 g·mol−1 |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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23 mg/kg (mice, intraperitoneal)[1] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
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TTFB (4,5,6,7-Tetrachloro-2-trifluoromethylbenzimidazole) is a halogenated benzimidazole derivative that acts as an uncoupling agent.[2]
See also
References
- ↑ Ilivicky, J; Casida, JE (June 1969). "Uncoupling action of 2,4-dinitrophenols, 2-trifluoromethylbenzimidazoles and certain other pesticide chemicals upon mitochondria from different sources and its relation to toxicity.". Biochemical Pharmacology 18 (6): 1389–401. doi:10.1016/0006-2952(69)90252-4. PMID 5799112.
- ↑ Beechey, RB (January 1966). "The uncoupling of respiratory-chain phosphorylation by 4,5,6,7-tetrachloro-2-trifluoromethylbenzimidazole.". The Biochemical Journal 98 (1): 284–9. doi:10.1042/bj0980284. PMID 4223043.
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