Chemistry:Spicamycin
From HandWiki
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| Names | |
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| IUPAC name
N-[2-[[2-(1,2-dihydroxyethyl)-4,5-dihydroxy-6-(7H-purin-6-ylamino)oxan-3-yl]amino]-2-oxoethyl]-14-methylpentadecanamide
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| Other names
Septacidin, NSC65104
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| Identifiers | |
3D model (JSmol)
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| ChEBI | |
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PubChem CID
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| Properties | |
| C30H51N7O7 | |
| Molar mass | 621.780 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
Spicamycin is an antibiotic with the molecular formula C30H51N7O7 which is produced by the bacterium Streptomyces alanosinicus.[1][2][3] Spicamycin also shows antitumor activity.[3]
References
- ↑ Burger, AM; Kaur, G; Hollingshead, M; Fischer, RT; Nagashima, K; Malspeis, L; Duncan, KL; Sausville, EA (March 1997). "Antiproliferative activity in vitro and in vivo of the spicamycin analogue KRN5500 with altered glycoprotein expression in vitro.". Clinical Cancer Research 3 (3): 455–63. PMID 9815705.
- ↑ "Septacidin" (in en). Pubchem.ncbi.NLM.nih.gov. https://pubchem.ncbi.nlm.nih.gov/compound/494023#section=Other-Identifiers.
- ↑ 3.0 3.1 Omura, Satoshi (6 December 2012) (in en). The Search for Bioactive Compounds from Microorganisms. Springer Science & Business Media. p. 107. ISBN 978-1-4612-4412-7.
Further reading
- Suzuki, Tamotsu; Suzuki, Sayaka T.; Yamada, Iwao; Koashi, Yoshiaki; Yamada, Kazue; Chida, Noritaka (1 May 2002). "Total Synthesis of Spicamycin". The Journal of Organic Chemistry 67 (9): 2874–2880. doi:10.1021/jo010925c. PMID 11975540.
- Suzuki, Tamotsu; Chida, Noritaka (February 2003). "The New and Efficient Synthesis of a Heptose Moiety of Spicamycin". Chemistry Letters 32 (2): 190–191. doi:10.1246/cl.2003.190.
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