Chemistry:Pyrrolidonyl-β-naphthylamide

From HandWiki
Pyrrolidonyl-β-naphthylamide
Pyrrolidonylbetanaphthylamide.png
Names
IUPAC name
N1-(Naphthalen-2-yl)-5-oxo-L-prolinamide
Systematic IUPAC name
(2S)-N-(Naphthalen-2-yl)-5-oxopyrrolidine-2-carboxamide
Other names
Pyrrolidonyl-beta-naphthylamide
Identifiers
3D model (JSmol)
ChemSpider
UNII
Properties
C15H14N2O2
Molar mass 254.289 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is ☑Y☒N ?)
Infobox references
Tracking categories (test):

Pyrrolidonyl-β-naphthylamide (PYR) is a molecule used in microbiology to detect the presence of pyrrolidonyl peptidase.[1] In the presence of bacteria with pyrrolidonyl peptidase, it is broken down to pyroglutamic acid and 2-naphthylamine. To detect this process, p-dimethylaminocinnamaldehyde is added and a change to a pink color can then be detected.

References

  1. Oberhofer, Thomas R. (1986). "Value of the l-pyrrolidonyl-β-naphthylamide hydrolysis test for identification of select gram-positive cocci". Diagnostic Microbiology and Infectious Disease 4: 43–47. doi:10.1016/0732-8893(86)90055-6.