Chemistry:Pyridine-3-carbaldehyde

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Short description: Organic compound
Pyridine-3-carbaldehyde
3-formylpyridine.svg
Names
Preferred IUPAC name
Pyridine-3-carbaldehyde
Other names
Nicotinaldehyde, 3-formylpyridine, 3-pyridinaldehyde
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
EC Number
  • 207-900-4
KEGG
UNII
Properties
C6H5NO
Molar mass 107.112 g·mol−1
Appearance colorless liquid
Density 1.14 g/cm3
Melting point 7 °C (45 °F; 280 K)
Boiling point 95–97 °C (203–207 °F; 368–370 K) 15 mm
Hazards
GHS pictograms GHS02: FlammableGHS05: CorrosiveGHS07: HarmfulGHS08: Health hazard
GHS Signal word Danger
H226, H302, H315, H317, H318, H334, H335, H341, H412
P201, P202, P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P272, P273, P280, P281, P285, P301+312, P302+352, P303+361+353, P304+340, P304+341, P305+351+338, P308+313, P310
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Pyridine-3-carbaldehyde is an organic compound with the formula C5H4NCHO. It is one of three isomeric pyridinaldehydes. The other isomers are pyridine-2-carboxaldehyde and pyridine-4-carboxaldehyde. It is a colorless liquid that is routinely available commercially. It can be produced from nicotinonitrile. Alternatively, it arises by the aerobic oxidation of the corresponding alcohol.[1]

Safety

3-Pyridinecarboxaldehyde is a severe skin irritant.[2]

References

  1. Marko, I. E.; Giles, P. R.; Tsukazaki, M.; Brown, S. M.; Urch, C. J. (1996). "Copper-Catalyzed Oxidation of Alcohols to Aldehydes and Ketones: An Efficient, Aerobic Alternative". Science 274 (5295): 2044–2046. doi:10.1126/science.274.5295.2044. PMID 8953027. 
  2. H. Stetter1, H. Kuhlmann, and G. Lorenz (1979). "Cyanide-Catalyzed Conjugate Addition of Aryl Aldehydes: 4-Oxo-4-(3-Pyridyl)Butyronitrile". Organic Syntheses 59: 53. doi:10.15227/orgsyn.059.0053.