Chemistry:Propagermanium

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Propagermanium
Propagermanium polymeric.png
Names
IUPAC name
3-[(2-Carboxyethyl-oxogermyl)oxy-oxogermyl]propanoic acid
Other names
proxigermanium, Ge-132, germanium sesquioxide, 2-carboxyethylgermasesquioxane, SK-818, bis(2-carboxyethylgermanium) sesquioxide
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
EC Number
  • 235-800-0
KEGG
UNII
Properties
C6H10O7Ge2
Molar mass 339.4222 g/mol
Hazards
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H315, H319, H335
P261, P264, P264+265Script error: No such module "Preview warning".Category:GHS errors, P271, P280, P302+352, P304+340, P305+351+338, P319Script error: No such module "Preview warning".Category:GHS errors, P321, P332+317Script error: No such module "Preview warning".Category:GHS errors, P337+317Script error: No such module "Preview warning".Category:GHS errors, P362+364Script error: No such module "Preview warning".Category:GHS errors, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Propagermanium (INN), also known by a variety of other names including bis(2-carboxyethylgermanium) sesquioxide and 2-carboxyethylgermasesquioxane, is an organometallic compound of germanium[2] that is sold as an alternative medicine. It is a polymeric compound with the formula ((HOOCCH2CH2Ge)2O3)n.

The compound was first synthesized in 1967 at the Asai Germanium Research Institute[3] in Japan . It is a water-soluble organogermanium compound used as raw material in health foods. The compound displays low toxicity in studies with rats.[4]

References

  1. "Bis (2-Carboxyethylgermanium)sesquioxide" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/83030#section=Safety-and-Hazards. 
  2. M.P. Egorov, P.P. Gaspar (1994), Germanium: Organometallic chemistry in Encyclopedia of Inorganic Chemistry. John Wiley & Sons ISBN:0-471-93620-0
  3. "Asai Germanium Japan" (in en-US). https://asaigermanium.com/. 
  4. Doi, Yuko (2017). "No carcinogenicity of poly-trans-[(2-carboxyethyl) germasesquioxane] (Ge-132): 26-week feeding study using rasH2 mice". Fundamental Toxicological Sciences 4 (3): 137–150. doi:10.2131/fts.4.137.