Chemistry:Nitecapone

From HandWiki
Short description: Chemical compound
Nitecapone
Skeletal formula
Space-filling model
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC12H11NO6
Molar mass265.221 g·mol−1
3D model (JSmol)

Nitecapone (INN; OR-462) is a drug which acts as a selective inhibitor of the enzyme catechol O-methyl transferase (COMT).[1][2] It was patented as an antiparkinson medication but was never marketed.[1]

See also

References

  1. 1.0 1.1 F.. Macdonald (1997). Dictionary of Pharmacological Agents. CRC Press. p. 1635. ISBN 978-0-412-46630-4. https://books.google.com/books?id=A0THacd46ZsC&pg=PA1435. Retrieved 20 May 2012. 
  2. "Inhibition of catechol-O-methyltransferase activity by two novel disubstituted catechols in the rat". European Journal of Pharmacology 153 (2–3): 263–9. August 1988. doi:10.1016/0014-2999(88)90614-0. PMID 3181288.