Chemistry:Niceritrol
From HandWiki
Short description: Chemical compound
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| Formula | C29H24N4O8 |
| Molar mass | 556.531 g·mol−1 |
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Niceritrol is a niacin derivative used as a hypolipidemic agent. It is an ester of pentaerythritol and nicotinic acid, has general properties similar to those of nicotinic acid (Nicotinamide), to which it is slowly hydrolysed. Niceritrol has been used as a lipid regulating drug in hyperlipidaemias and as a vasodilator in the treatment of peripheral vascular disease.[1][2]
References
- ↑ "Antiproteinuric effect of niceritrol, a nicotinic acid derivative, in chronic renal disease with hyperlipidemia: a randomized trial". The American Journal of Medicine 114 (5): 347–53. April 2003. doi:10.1016/s0002-9343(02)01567-x. PMID 12714122. http://www.amjmed.com/article/S0002-9343(02)01567-X/abstract.
- ↑ Truven Health Analytics Inc. (May 8, 2008). "Niceritrol". Micromedexsolutions.com. http://www.micromedexsolutions.com/micromedex2/librarian/ND_T/evidencexpert/ND_PR/evidencexpert/CS/CAA11B/ND_AppProduct/evidencexpert/DUPLICATIONSHIELDSYNC/10C889/ND_PG/evidencexpert/ND_B/evidencexpert/ND_P/evidencexpert/PFActionId/evidencexpert.IntermediateToDocumentLink?docId=9258-x&contentSetId=30&title=Niceritrol&servicesTitle=Niceritrol.
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