Chemistry:Minodronic acid

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Minodronic acid
Minodronic acid.svg
Names
Preferred IUPAC name
[1-Hydroxy-2-(imidazo[1,2-a]pyridin-3-yl)ethane-1,1-diyl]bis(phosphonic acid)
Other names
Minodronate; YM 529
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
Properties
C9H12N2O7P2
Molar mass 322.150 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Minodronic acid is a third-generation bisphosphonate drug. It is approved for use in Japan for the treatment of osteoporosis.[1] Its mechanism of action involves inhibition of farnesyl pyrophosphate synthase activity.[2]

References

  1. Shridhar Hegde and Michelle Schmidt (2009). "To Market, To Market - 2009. 16. Minodronic acid". Annual Reports in Medicinal Chemistry 45: 509–510. doi:10.1016/s0065-7743(10)45028-9. 
  2. Sorbera, L.A.; Castañer, J.; Leeson, P.A. (2002). "Minodronic Acid". Drugs of the Future 27 (10): 935–941. doi:10.1358/dof.2002.027.10.701186.