Chemistry:Kalium Database

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Short description: Scientific database
Kalium Database
Kalium Database Logo.png
Type of site
Biomedical database
Available in
  • English
FoundedRussian Academy of Sciences, Moscow, Russia
Created byAlexey I. Kuzmenkov
Nikolay A. Krylov
Daria A. Yureva
Valentin M. Tabakmakher
Anton O. Chugunov
Alexander A. Vassilevski
Websitekaliumdb.org
LaunchedApril 16, 2016; 8 years ago (2016-04-16)
Current statusActive

The Kalium Database is a manually curated biomedical database on K+ channel ligands found in the venom of scorpions, spiders, sea anemones, cone snails, snakes, centipedes, bees, and more.[1] The first release of the Kalium Database was dedicated to scorpion toxins only,[2] while its second release (Kalium 2.0) included toxins from other living organisms.[3] The most recent update (Kalium 3.0) added information on their artificial derivatives. The Kalium Database is meant to assist structural biologists, toxinologists, pharmacologists, medicinal chemists, and other researchers in their pursuit to develop new drugs for cardiovascular and neurological diseases.

References

  1. "Diversity of Potassium Channel Ligands: Focus on Scorpion Toxins". Biochemistry (Mosc) 80 (13): 1764–99. Dec 2015. doi:10.1134/S0006297915130118. PMID 26878580. 
  2. "Kalium: a database of potassium channel toxins from scorpion venom". Database (Oxford) baw056: baw056. Apr 2016. doi:10.1093/database/baw056. PMID 27087309. 
  3. "Kalium 2.0, a comprehensive database of polypeptide ligands of potassium channels". Sci Data 6 (1): 73. May 2019. doi:10.1038/s41597-019-0074-x. PMID 31133708. Bibcode2019NatSD...6...73T.