Chemistry:JNJ-28330835

From HandWiki
Short description: Chemical compound
JNJ-28330835
JNJ-28330835 structure.png
Legal status
Legal status
  • US: Investigational drug
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC14H10F6N4O
Molar mass364.25 g·mol−1
3D model (JSmol)

JNJ-28330835 is a drug which acts as a selective androgen receptor modulator (SARM). In studies on rats it was found to enhance muscle growth and sexual behavior but with minimal effects on prostate gland size. A number of related compounds are known, though JNJ-28330835 has progressed furthest through development.[1][2]

References

  1. "Serendipitous discovery of novel imidazolopyrazole scaffold as selective androgen receptor modulators". Bioorganic & Medicinal Chemistry Letters 17 (2): 439–43. January 2007. doi:10.1016/j.bmcl.2006.10.035. PMID 17079140. 
  2. "A selective androgen receptor modulator with minimal prostate hypertrophic activity enhances lean body mass in male rats and stimulates sexual behavior in female rats". Endocrine 32 (1): 41–51. August 2007. doi:10.1007/s12020-007-9005-2. PMID 17992601.