Chemistry:Isodesmosine

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Isodesmosine
Isodesmosine.svg
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
MeSH D007524
Properties
C24H40N5O8
Molar mass 526.611 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Isodesmosine is a lysine derivative found in elastin. Isodesmosine is an isomeric pyridinium-based amino acid resulting from the condensation of four lysine residues between elastin proteins by lysyl-oxidase. These represent ideal biomarkers for monitoring elastin turnover because these special cross-links are only found in mature elastin in mammals.[1]

See also

References

  1. Miao, M.; Bruce, A.E.E.; Bhanji, T.; Davis, E.C.; Keeley, F.W. (2007). "Differential expression of two tropoelastin genes in zebrafish". Matrix Biology 26 (2): 115–124. doi:10.1016/j.matbio.2006.09.011. PMID 17112714.