Chemistry:Hydrocholeretic

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Hydrocholeretics are substances that increase the volume of secretion of bile from the liver without increasing the amount of solids secreted.[1] Some substances can result in decreased solid production, possibly due to circulatory effects.[2] Cyclobutyrol is a compound commonly used as a hydrocholeretic. Its effects in rats include a dose-dependent increase in bile flow, sodium, potassium, chloride and bicarbonate outputs and reduced bile acid concentrations.[3]

See also

References

  1. ↑ Textbook of Biochemistry and Human Biology, by G. P. Talwar, Talwar & Srivastava (eds.), L. M. Srivastava, p.610.
  2. ↑ Brauer, R. W.; Pessotti, R. L. (1952). "The Effect of Choleretic and of Hydrocholeretic Agents on Bile Flow and Bile Solids in the Isolated Perfused Liver". Science 115 (2980): 142–143. doi:10.1126/science.115.2980.142. PMID 14913193. Bibcode: 1952Sci...115..142B. 
  3. ↑ Monte, MJ (1990). "Choleretic mechanism and effects of cyclobutyrol in the rat: dose-response relationship.". Biomed Biochim Acta 49 (1): 83–90. PMID 2360911. 



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