Chemistry:Fludroxycortide

Short description: Chemical compound

Fludroxycortide

Clinical data
Trade names	Cordran, Haelan
Other names	6α-Fluoro-16α-hydroxyhydrocortisone 16,17-acetonide; 6α-Fluoro-11β,16α,17α,21-tetrahydroxypregn-4-ene-3,20-dione 16,17-acetonide
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Routes of administration	Topical
ATC code	D07AC07 (WHO)
Legal status
Legal status	UK: POM (Prescription only)
Identifiers
IUPAC name 6-Fluoro-11,21-dihydroxy-16,17-[(l-methylethylidene)bis(oxy)]-(6α,11β,16α)-pregn-4-ene-3,20-dione
CAS Number	1524-88-5 Y
PubChem CID	15209
IUPHAR/BPS	7606
DrugBank	DB00846 Y
ChemSpider	14475 Y
UNII	8EUL29XUQT
KEGG	D00328 Y
ChEMBL	ChEMBL1201012 N
Chemical and physical data
Formula	C24H33FO6
Molar mass	436.520 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C1\C=C5/[C@](C)(CC1)[C@@H]2[C@H]([C@H]3[C@](C[C@@H]2O)([C@@]4(OC(O[C@@H]4C3)(C)C)C(=O)CO)C)C[C@@H]5F
InChI InChI=1S/C24H33FO6/c1-21(2)30-19-9-14-13-8-16(25)15-7-12(27)5-6-22(15,3)20(13)17(28)10-23(14,4)24(19,31-21)18(29)11-26/h7,13-14,16-17,19-20,26,28H,5-6,8-11H2,1-4H3/t13-,14-,16-,17-,19+,20+,22-,23-,24+/m0/s1 Y Key:POPFMWWJOGLOIF-XWCQMRHXSA-N Y
NY (what is this?)  (verify)

Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US).

Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses.