Chemistry:Etofamide

Etofamide
Clinical data
AHFS/Drugs.com	International Drug Names
Routes of; administration	Oral
ATC code	P01AC03 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Identifiers
	IUPAC name 2,2-dichloro-N-(2-ethoxyethyl)-N- [4-(4-nitrophenoxy)benzyl]acetamide;
CAS Number	25287-60-9 ;
PubChem CID	65718;
ChemSpider	59142;
UNII	03F36JH21U;
KEGG	D07355 ;
ChEMBL	ChEMBL1788393;
Chemical and physical data
Formula	C19H20Cl2N2O5
Molar mass	427.28 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CCOCCN(CC1=CC=C(C=C1)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(Cl)Cl;
	InChI InChI=1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3; Key:QTRALMGDQMIVFF-UHFFFAOYSA-N;
	(verify)

Short description: Chemical compound

Etofamide (INN, also known as eticlordifene) is an antiprotozoal drug used in the treatment of amoebiasis.

Its effect against Giardia lamblia has been described as modest.^[1]

References

↑ "In-vitro susceptibility of Giardia lamblia to albendazole, mebendazole and other chemotherapeutic agents". Journal of Medical Microbiology 37 (3): 221–4. September 1992. doi:10.1099/00222615-37-3-221. PMID 1518040.

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Clinical data

AHFS/Drugs.com	International Drug Names
Routes of administration	Oral
ATC code	P01AC03 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Identifiers
IUPAC name 2,2-dichloro-N-(2-ethoxyethyl)-N- [4-(4-nitrophenoxy)benzyl]acetamide
CAS Number	25287-60-9^Y
PubChem CID	65718
ChemSpider	59142
UNII	03F36JH21U
KEGG	D07355^Y
ChEMBL	ChEMBL1788393
Chemical and physical data
Formula	C₁₉H₂₀Cl₂N₂O₅
Molar mass	427.28 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES CCOCCN(CC1=CC=C(C=C1)OC2=CC=C(C=C2)[N+](=O)[O-])C(=O)C(Cl)Cl
InChI InChI=1S/C19H20Cl2N2O5/c1-2-27-12-11-22(19(24)18(20)21)13-14-3-7-16(8-4-14)28-17-9-5-15(6-10-17)23(25)26/h3-10,18H,2,11-13H2,1H3 Key:QTRALMGDQMIVFF-UHFFFAOYSA-N
(verify)