Chemistry:Ethylene bis(iodoacetate)
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| Names | |
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| Preferred IUPAC name
Ethane-1,2-diyl bis(iodoacetate) | |
| Other names
Ethane-1,2-diyl bis(2-iodoacetate)
S-10 | |
| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C6H8I2O4 | |
| Molar mass | 397.935 g·mol−1 |
| Hazards | |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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16.1 mg/kg (mice, intraperitoneal) 4.94 mg/kg (dogs, intravenous) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Ethylene bis(iodoacetate), also known as S-10, is the iodoacetate ester of ethylene glycol. It's an alkylating agent that has been studied as an anticancer drug.[1]
See also
References
- ↑ "Enzyme Alterable Alkylating Agents. VI. Synthesis, Chemical Properties, Toxicities, and Clinical Trial of Haloacetates and Haloacetamides Containing Enzyme-Susceptible Bonds". JNCI: Journal of the National Cancer Institute. August 1963. doi:10.1093/jnci/31.2.297.
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