Chemistry:Epomediol

From HandWiki
Short description: Synthetic terpenoid
Epomediol
Skeletal formula
Ball-and-stick model
Clinical data
Other names1,3,3-Trimethyl-2-oxabicyclo [2.2.2]octane-6,7-endo,endo-diol
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC10H18O3
Molar mass186.251 g·mol−1
3D model (JSmol)

Epomediol (trade name Clesidren) is a synthetic terpenoid with choleretic effects. It has been used in the symptomatic treatment of itching due to intrahepatic cholestasis of pregnancy.[1][2][3]

References

  1. "Epomediol ameliorates pruritus in patients with intrahepatic cholestasis of pregnancy". J Hepatol 16 (1–2): 241–2. September 1992. doi:10.1016/S0168-8278(05)80122-9. PMID 1484159. 
  2. Reyes H (December 1992). "The spectrum of liver and gastrointestinal disease seen in cholestasis of pregnancy". Gastroenterol Clin North Am 21 (4): 905–21. PMID 1478743. 
  3. "Intrahepatic cholestasis of pregnancy: an estrogen-related disease". Semin Liver Dis 13 (3): 289–301. August 1993. doi:10.1055/s-2007-1007357. PMID 8235718.