Chemistry:Dimethylbenzimidazole

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Dimethylbenzimidazole
5,6-Dimethylbenzimidazole.svg
Names
Preferred IUPAC name
5,6-Dimethyl-1H-benzimidazole
Identifiers
3D model (JSmol)
116595
ChEBI
ChEMBL
ChemSpider
DrugBank
EC Number
  • 209-488-1
279255
KEGG
UNII
Properties
C9H10N2
Molar mass 146.193 g·mol−1
Hazards
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H302, H315, H319, H335, H412
P261, P264, P270, P271, P273, P280, P301+312, P302+352, P304+340, P305+351+338, P312, P321, P330, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

5,6-Dimethylbenzimidazole is a natural benzimidazole derivative. It is a component of vitamin B12 where is serves as a ligand for the cobalt atom.[1]

5,6-Dimethylbenzimidazole is biosynthesized from flavin mononucleotide by the enzyme 5,6-dimethylbenzimidazole synthase.[2]

References

  1. Barker, HA; Smyth, RD; Weissbach, H; Toohey, JI; Ladd, JN; Volcani, BE (1960). "Isolation and properties of crystalline cobamide coenzymes containing benzimidazole or 5, 6-dimethylbenzimidazole". The Journal of Biological Chemistry 235 (2): 480–8. doi:10.1016/S0021-9258(18)69550-X. PMID 13796809. 
  2. "5,6-Dimethylbenzimidazole biosynthesis". MetaCyc. http://www.biocyc.org/META/NEW-IMAGE?type=PATHWAY&object=PWY-5523.