Chemistry:Deterenol

From HandWiki
Short description: Chemical compound
Deterenol
Deterenol.svg
Clinical data
Trade namesBetafrine
Other namesIsopropylnorsynephrine, Isopropyloctopamine
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC11H17NO2
Molar mass195.262 g·mol−1
3D model (JSmol)

Deterenol (also known as Isopropylnorsynephrine and Isopropyloctopamine; trade name Betaphrine) is a stimulant drug which acts as a beta agonist. It has been found as an ingredient of dietary supplement products, but is banned in most countries due to risk of cardiac arrest.[1][2][3][4][5]

See also

References

  1. "The sympathomimetic activity of N-isopropyloctopamine in vitro". The Journal of Pharmacology and Experimental Therapeutics 225 (3): 553–8. June 1983. PMID 6306210. 
  2. "Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium". Journal of Physiology and Biochemistry 67 (3): 443–52. September 2011. doi:10.1007/s13105-011-0078-2. PMID 21336650. 
  3. "A cocktail of synthetic stimulants found in a dietary supplement associated with serious adverse events". Drug Testing and Analysis 6 (6): 578–81. June 2014. doi:10.1002/dta.1664. PMID 24802503. 
  4. "Detection and quantification of phenethylamines in sports dietary supplements by NMR approach". Journal of Pharmaceutical and Biomedical Analysis 151: 347–355. March 2018. doi:10.1016/j.jpba.2018.01.025. PMID 29413984. 
  5. "Nine prohibited stimulants found in sports and weight loss supplements: deterenol, phenpromethamine (Vonedrine), oxilofrine, octodrine, beta-methylphenylethylamine (BMPEA), 1,3-dimethylamylamine (1,3-DMAA), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylbutylamine (1,3-DMBA) and higenamine". Clinical Toxicology 59 (11): 975–981. March 2021. doi:10.1080/15563650.2021.1894333. PMID 33755516.