Chemistry:Debacterol
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| sulfuric acid | Mineral acid |
| Phenolsulfonic acid | Sulfonic acid |
| sulfonated phenolic compound | wood creosote |
| Clinical data | |
| Routes of administration | Topical |
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Debacterol Canker Sore Pain Relief solution is a liquid topical agent that is used in the treatment of ulcerating oral mucosal lesions and minor oral abrasions.[1]
Description
Debacterol is used[2] in the treatment of recurrent aphthous stomatitis (canker sores). Debacterol usually comes in a swab form, but is also available in a vial.
Debacterol is not listed in the Physician's Desk Reference comprehensive list of prescription drugs[3]. Debacterol has not been tested or been proven to be safe and effective by the Food and Drug Administration[4]. Debacterol is not an antiseptic or anesthetic topical agent. It is a mixture of powerful acids that function as a chemical cautery to destroy all cells at the application site, including the nerve endings that transmit pain.
Effectiveness
One clinical trial comparing Debacterol to Kenalog-in-Orabase and a no-intervention control group found that patients treated with Debacterol reported significantly better relief of symptoms compared to the other two groups 3 days after treatment.[5] In the same study, 60% of ulcers treated with Debacterol had disappeared by day 6 compared to about 30% in the other groups.[5]
Debacterol appears to be more effective on mouth sores in areas of the mouth which have less saliva production. Since a mouth sore must be dry prior to application of Debacterol, the area under the tongue is difficult to get a solid application on. The length of time of pain relief and the overall effectiveness may be reduced in areas such as this.
References
- ↑ "Debacterol product description". http://www.debacterol.com/prod_desc.html.
- ↑ "The Miracle Canker Sore Remedy That Most Physicians Have Never Heard Of". October 2013. http://www.skinsight.com/info/blog/2013/10/16/miracle-canker-sore-remedy-most-physicians-have-never-heard.
- ↑ "PDR.Net (The Physician's Desk Reference)" (in en). http://www.pdr.net.
- ↑ "Search Results: debacterol". https://google2.fda.gov/search?q=debacterol&client=FDAgov&site=FDAgov&lr=&proxystylesheet=FDAgov&requiredfields=-archive:Yes&output=xml_no_dtd&getfields=*.
- ↑ 5.0 5.1 Rhodus, NL; Bereuter, J (December 1998). "An evaluation of a chemical cautery agent and an anti-inflammatory ointment for the treatment of recurrent aphthous stomatitis: a pilot study.". Quintessence international (Berlin, Germany : 1985) 29 (12): 769–73. PMID 10196853.
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