Chemistry:Chrome Azurol S

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Short description: Microbial stain
Chrome Azurol S
Chrome Azurol S.svg
Names
Preferred IUPAC name
Trisodium 5-[(E)-(3-carboxy-5-methyl-4-oxocyclohexa-2,5-dien-1-ylidene)(2,6-dichloro-3-sulfonatophenyl)methyl]-3-methyl-2-oxidobenzoate
Other names
  • Mordant Blue 29
  • C.I. 43825
  • Alberon
Identifiers
3D model (JSmol)
UNII
Properties
C23H13Cl2Na3O9S
Molar mass 605.28 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Chrome Azurol S is a histological dye used in biomedical research.[1][2]

Chrome Azural S (CAS) is a common spectrophotometric reagent for detection of certain metals like aluminum which can be toxic in excess and can contribute to people with neurodegenerative disorders.[3] CAS is used to provide quantitative and qualitative information on molecules of interest like aluminum and siderophores.[4] Qualitatively a color change can be observed while also allowing to quantitatively determine concentration of certain ions.

References

  1. Berger, Selman A.; McKay, J. Brian (July 1974). "The photometric titration of Fe(III) with EDTA using tiron indicator". Microchimica Acta 62 (4): 665–670. doi:10.1007/bf01218204. PMID 4216747. 
  2. Alexander, D.; Zuberer, David (1991-09-01). "Use of chrome azurol S reagents to evaluate siderophore production by rhizosphere bacteria". Biology and Fertility of Soils 12: 39–45. doi:10.1007/BF00369386. 
  3. Ngarisan, Noor Izyan; Ngah, Che Wan Zanariah Che Wan; Ahmad, Musa; Kuswandi, Bambang (2014-11-01). "Optimization of polymer inclusion membranes (PIMs) preparation for immobilization of Chrome Azurol S for optical sensing of aluminum(III)" (in en). Sensors and Actuators B: Chemical 203: 465–470. doi:10.1016/j.snb.2014.07.023. ISSN 0925-4005. https://www.sciencedirect.com/science/article/pii/S092540051400851X. 
  4. Himpsl, Stephanie D.; Mobley, Harry L. T. (2019). "Siderophore Detection Using Chrome Azurol S and Cross-Feeding Assays". Proteus mirabilis. Methods in Molecular Biology. 2021. pp. 97–108. doi:10.1007/978-1-4939-9601-8_10. ISBN 978-1-4939-9600-1. https://pubmed.ncbi.nlm.nih.gov/31309499/#:~:text=The%20chrome%20azurol%20S%20(CAS,change%20from%20blue%20to%20orange..