Chemistry:Chlorosipentramine

From HandWiki
Short description: Chemical compound
Chlorosipentramine
Chlorosipentramine structure.png
Identifiers
Chemical and physical data
FormulaC18H27Cl2N
Molar mass328.32 g·mol−1
3D model (JSmol)

Chlorosipentramine is an analogue of the anorectic drug sibutramine, which has been sold as an ingredient in weight loss products sold as dietary supplements, first detected in South Korea in 2017.[1] It is one of a number of sibutramine derivatives which have been sold in grey-market weight loss products since sibutramine itself was taken off the market due to safety concerns. Others include desmethylsibutramine, didesmethylsibutramine, homosibutramine, chlorosibutramine, and benzylsibutramine.[2][3] Chlorosipentramine is illegal in South Korea along with other related compounds.[4][5]

See also

References

  1. "Isolation and structural characterization of a novel sibutramine analogue, chlorosipentramine, in a slimming dietary supplement, by using HPLC-PDA, LC-Q-TOF/MS, FT-IR, and NMR". Forensic Science International 286: 199–207. May 2018. doi:10.1016/j.forsciint.2018.03.021. PMID 29602147. 
  2. "Metabolic analysis of the illegal analogues of anti-obesity drugs using LC-Q-TOF-MS/MS". Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 1163: 122502. January 2021. doi:10.1016/j.jchromb.2020.122502. PMID 33412503. 
  3. "Application of liquid chromatography-high resolution mass spectrometry and liquid chromatography-tandem mass spectrometry methods to 45 weight loss compounds in health functional food, food, and illegal drug". Journal of Separation Science 45 (15): 2795–2803. August 2022. doi:10.1002/jssc.202101030. PMID 35614582. 
  4. "Ministry ferrets out fake erectile dysfunction, obesity drugs". Korea Biomedical Review. 19 July 2017. https://www.koreabiomed.com/news/articleView.html?idxno=912. 
  5. "Anti-obesity drugs and their analogues: Chlorosipentramine". https://faolex.fao.org/docs/pdf/kor190522.pdf.