Chemistry:Chaetoxanthone

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Chaetoxanthone
Chaetoxanthone A.svg
Chaetoxanthone A
Chaetoxanthone B.svg
Chaetoxanthone B
Chaetoxanthone C.svg
Chaetoxanthone C
Chaetoxanthone D.svg
Chaetoxanthone D
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

Chaetoxanthones are a class of chemical compounds which are classified as xanthones. They have been isolated from marine-derived fungi in the genus Chaetomium.[1] There are four compounds in the class that are designated as chaetoxanthones A through D.[1][2] A laboratory synthesis of (±)-chaetoxanthone B has been reported.[3] The chaetoxanthones are under investigation as potential antimalarials.[3]

References

  1. 1.0 1.1 Pontius, Alexander; Krick, Anja; Kehraus, Stefan; Brun, Reto; König, Gabriele M. (1 September 2008). "Antiprotozoal Activities of Heterocyclic-Substituted Xanthones from the Marine-Derived Fungus Chaetomium sp.". Journal of Natural Products 71 (9): 1579–1584. doi:10.1021/np800294q. PMID 18683985. 
  2. Wang, Meng-Hua; Li, Li; Jiang, Tao; Wang, Xue-Wei; Sun, Bin-Da; Song, Bo; Zhang, Qiu-Bo; Jia, Hong-Mei et al. (2015). "Stereochemical determination of tetrahydropyran-substituted xanthones from fungus Chaetomium murorum". Chinese Chemical Letters 26 (12): 1507–1510. doi:10.1016/j.cclet.2015.10.025. 
  3. 3.0 3.1 Lennon, Amber C.; Tallen, Sara C.; Dabire, Sadiq W.; Quach, Nhu H.; Gladen, Paul T. (October 2021). "Total synthesis of (±)-chaetoxanthone B". Tetrahedron Letters 82: 153390. doi:10.1016/j.tetlet.2021.153390.