Chemistry:Benzylpenicilloyl polylysine

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Short description: Chemical compound
Benzylpenicilloyl polylysine
Benzylpenicilloyl polylysine (structural diagram).png
Clinical data
Trade namesPre-Pen
Other namesPre-Pen
License data
Routes of
administration
Liquid intradermal
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
DrugBank
ChemSpider
  • none
UNII
ChEMBL
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Benzylpenicilloyl polylysine (Pre-Pen) is used as a skin test before the administration of penicillin. It is used to detect the immunoglobulin E antibodies.[1][2] The chemical structure consists of the benzylpenicilloyl group attached to a polymer of L-lysine.[3][4][5]

References

  1. "Benzylpenicilloyl polylysine". PharmGKB. http://www.pharmgkb.org/do/serve?objId=PA164754810&objCls=Drug. 
  2. "Benzylpenicilloyl polylysine". DrugBank. http://www.drugbank.ca/drugs/DB00895. 
  3. "Preparation of benzylpenicilloyl-polylysine: a preliminary study". Allergy and Asthma Proceedings 25 (3): 165–168. 2004. PMID 15317320. 
  4. "The preparation and determination of structure of benzylpenicilloyl compounds used in skin-testing for penicillin allergy". The Journal of Antibiotics 36 (6): 709–714. June 1983. doi:10.7164/antibiotics.36.709. PMID 6874593. 
  5. "PRE-PEN® (benzylpenicilloyl polylysine injection USP) Skin Test Antigen". DailyMed. U.S. National Library of Medicine. https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=2fbcc40c-f102-4abe-bce5-a93de95874fe&type=display.