Chemistry:AP-238

From HandWiki
Short description: Opioid designer drug
AP-238
AP-238.svg
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC18H26N2O
Molar mass286.419 g·mol−1
3D model (JSmol)

AP-238 is an opioid designer drug related to drugs such as azaprocin and bucinnazine, with around the same potency as morphine.[2] It was first discovered in Italy in the 1960s but was never marketed,[3] subsequently appearing on the illicit market around 2020 and being detected in both Slovenia and the USA.[4][5]

See also

References

  1. "2-Methyl-AP-237". U.S Drug Enforcement Administration. https://deadiversion.usdoj.gov/drug_chem_info/2-Methyl-AP-237.pdf. 
  2. "Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238". Archives of Toxicology 96 (6): 1701–1710. June 2022. doi:10.1007/s00204-022-03257-7. PMID 35275255. 
  3. "2,6-Dialkylpiperazines. IV. 1-Propionyl-4-substituted cis-2,6-dimethylpiperazines structurally related to the analgetic 8-acyl-3,8-diazabicyclo[3.2.1]octanes". Journal of Medicinal Chemistry 11 (3): 592–594. May 1968. doi:10.1021/jm00309a039. PMID 5656502. 
  4. {{cite web | url = https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/AP-238-ID-2185-20_report.pdf | title = Analytical Report. AP-238. 1-{2,6‐dimethyl‐4‐[(2E)‐3‐phenylprop‐2‐en‐1‐yl]piperazin‐1‐yl}propan-1-one. | work =Nacionalni Forenzični Laboratorij | date = 20 October 2020 }}
  5. "AP-238". NPS Discovery at CFSRE. Center for Forensic Science Research and Education (CFSRE). 11 November 2020. https://www.npsdiscovery.org/wp-content/uploads/2020/11/AP-238_111120_CFSRE-Toxicology_Report.pdf.