Chemistry:6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide

From HandWiki
Short description: Chemical compound


6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide
CEPC structure.png
Identifiers
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC16H16ClN3O2
Molar mass317.77 g·mol−1
3D model (JSmol)

6-Chloro-5-ethoxy-N-(pyridin-2-yl)indoline-1-carboxamide (CEPC) is a drug which acts as a potent and selective antagonist for the serotonin 5-HT2C receptor. In animal studies it was found to potentiate the conditioned place preference induced by low-dose amphetamine, demonstrating that 5-HT2C-mediated disinhibition of dopamine release can cause interactions with dopaminergic drugs.[1]

See also

  • RS-102,221
  • SB-242,084
  • SCQ1

References

  1. ↑ "A 5-HT(2C) receptor antagonist potentiates a low dose amphetamine-induced conditioned place preference". Neuroscience Letters 505 (1): 10–3. November 2011. doi:10.1016/j.neulet.2011.07.036. PMID 21827831. 



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