Chemistry:6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate
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Short description: Fluorogenic amine labelling dye
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| Names | |
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| IUPAC name
(2,5-dioxopyrrolidin-1-yl) N-quinolin-6-ylcarbamate
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| Other names
6-AQC, AQC
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C14H11N3O4 | |
| Molar mass | 285.259 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
6-Aminoquinolyl-N-hydroxysuccinimidyl carbamate (AQC) is a fluorogenic, amine labeling dye that is not fluorescent itself, but covalently reacts with secondary amines to form a fluorescently labeled product.[2] It has a fluorescence excitation wavelength of 250 nm (UV-C), and emission wavelength of 395 nm (deep violet, near UV).[3]
See also
References
- ↑ "2,5-Dioxopyrrolidin-1-yl quinolin-6-ylcarbamate". National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/2762553.
- ↑ Stoyanov, Alexander V.; Ahmadzadeh, Hossein; Krylov, Sergey N. (2002-11-25). "Heterogeneity of protein labeling with a fluorogenic reagent, 3-(2-furoyl)quinoline-2-carboxaldehyde". Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 780 (2): 283–287. doi:10.1016/s1570-0232(02)00535-4. ISSN 1570-0232. PMID 12401353. https://pubmed.ncbi.nlm.nih.gov/12401353/.
- ↑ Cohen, S.A.; Michaud, D.P. (1993). "Synthesis of a Fluorescent Derivatizing Reagent, 6-Aminoquinolyl-N-Hydroxysuccinimidyl Carbamate, and Its Application for the Analysis of Hydrolysate Amino Acids via High-Performance Liquid Chromatography". Analytical Biochemistry (Elsevier BV) 211 (2): 279–287. doi:10.1006/abio.1993.1270. ISSN 0003-2697. PMID 8317704.
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