Chemistry:5-Fluoro-DET
From HandWiki
Short description: Chemical compound
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| Formula | C14H19FN2 |
| Molar mass | 234.318 g·mol−1 |
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5-Fluoro-DET (5F-DET, 5-fluoro-N,N-diethyltryptamine) is a tryptamine derivative related to drugs such as DET and 5-MeO-DET.[1][2] It acts as an inhibitor of the enzyme myeloperoxidase,[3] and is also thought to be an agonist at the 5-HT2A receptor.[4]
See also
- 5F-DMT
- 5F-MET
- 5F-EPT
- 6F-DET
References
- ↑ "1067. N-alkylated 5-fluorotryptamines.". Journal of the Chemical Society (Resumed): 5418–5421. 1961. doi:10.1039/JR9610005418.
- ↑ "Synthesis and pharmacological activity of alkylated tryptamines". Journal of Medicinal Chemistry 9 (3): 341–4. May 1966. doi:10.1021/jm00321a017. PMID 5960901.
- ↑ "Structure-based design, synthesis, and pharmacological evaluation of 3-(aminoalkyl)-5-fluoroindoles as myeloperoxidase inhibitors". Journal of Medicinal Chemistry 53 (24): 8747–59. December 2010. doi:10.1021/jm1009988. PMID 21090682. https://dipot.ulb.ac.be/dspace/bitstream/2013/74263/1/JMC_53_8747.pdf.
- ↑ Kruegel AC, Sporn J, "Specific Tryptamines for use in the Treatment of Mood Disorders.", WO patent 2021/168082, published 26 August 2021, assigned to Gilgamesh Pharmaceuticals, Inc..
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