Chemistry:4-(4-Methylphenyl)-4-oxobutanoic acid

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4-(4-Methylphenyl)-4-oxobutanoic acid
MMePhOxoBuacid.png
MMePhOxoBuacid3D.png
Names
Preferred IUPAC name
4-(4-Methylphenyl)-4-oxobutanoic acid
Other names
3-(4-Methylbenzoyl)propionic acid
3-(p-Toluoyl)propionic acid
4-(4-Methylphenyl)-4-oxobutyric acid
Identifiers
3D model (JSmol)
ChemSpider
EC Number
  • 610-285-9
UNII
Properties
C11H12O3
Molar mass 192.214 g·mol−1
Appearance White powder
Melting point 129 °C (264 °F; 402 K)
Insoluble
Hazards[1]
Main hazards Flammable
GHS pictograms GHS07: Harmful
GHS Signal word Warning
H315, H319, H335
P261, P264, P271, P280, P302+352, P304+340, P305+351+338, P312, P332+313, P337+313, P362, P403+233, P405, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

4-(4-Methylphenyl)-4-oxobutanoic acid is an organic carboxylic acid. The preparation of it is used for undergraduate teaching of organic chemistry synthesis.

Preparation

4-(4-Methylphenyl)-4-oxobutanoic acid can be prepared by a Friedel–Crafts reaction between toluene and succinic anhydride catalyzed by a Lewis acid such as aluminium chloride.[2]

References

  1. "3-(4-Methylbenzoyl)propionic acid" (in en). https://pubchem.ncbi.nlm.nih.gov/compound/244162#section=Safety-and-Hazards. 
  2. Preparation of 4-(p-methylphenyl)-4-oxobutanoic acid, Li Cuijuan, Lv Mingquan, Han Shuying, Xu Tanfeng (College of Chemistry and Molecule Engineering, Peking University), College Chemistry, Vol 20. Period 2.