Chemistry:2-Methyl-2-propyl-1,3-propanediol

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Short description: Chemical compound
2-Methyl-2-propyl-1,3-propanediol
2methyl2propylpropanediol structure.png
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC7H16O2
Molar mass132.203 g·mol−1
3D model (JSmol)
Melting point56–59 °C (133–138 °F)

2-Methyl-2-propyl-1,3-propanediol (MPP) is a simple alkyl diol which has sedative, anticonvulsant and muscle relaxant effects. It is both a synthetic precursor to, and an active metabolite of the tranquilizers meprobamate and carisoprodol, as well as other derivatives.[1][2][3][4]

See also

References

  1. "A nitrate ester of sedative alkyl alcohol improves muscle function and structure in a murine model of Duchenne muscular dystrophy". Molecular Pharmaceutics 10 (10): 3862–70. October 2013. doi:10.1021/mp400310r. PMID 23924275. 
  2. "Muscle-relaxing Compounds Similar to 3-(o-Toloxy)-1, 2-propanediol. 1 I. Aromatic Ethers of Polyhydroxy Alcohols and Related Compounds.". Journal of the American Chemical Society 72 (8): 3710–6. August 1950. doi:10.1021/ja01164a108. 
  3. Kato K, Tsukamoto K, "2-(2-Alkenyl)-1,3-propanediols and preparation of 2,2-disubstituted-1,3-propanediols", JP patent 09031000, issued 1997
  4. "Catalytic Hydrogenation of Cyclic Carbonates using Manganese Complexes". Angewandte Chemie International Edition in English 57 (41): 13449–13453. October 2018. doi:10.1002/anie.201808676. PMID 30134081.