Biology:Zeus (gene)
From HandWiki
Short description: Male fertility gene in Drosophila
Zeus (aliases Dmel\Rcd-1r, Rcd-1 related/Rcd-1r, CG9573, Drcd-1r/Drcd-1 related)[1] is a male fertility gene in Drosophila,[2][3][1] known especially from D. melanogaster[1] and D. simulans.[2] Zeus arose via a retrotransposition from Caf40,[3] a DNA-binding protein.[2] It differs by 107 amino acid substitutions.[2] It retains approximately 30% of Caf40's DNA-binding sites but over the past perhaps 4-6 million years has acquired another 193.[2] These new binding actions regulate hundreds of downstream reproduction related genes.[2][3] Disruption of this gene disrupts testicle and sperm development.[2]
References
- ↑ 1.0 1.1 1.2 "FlyBase Gene Report: Dmel\Rcd-1r". 2021-10-15. http://flybase.org/reports/FBgn0032089.html.
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Long, Manyuan; VanKuren, Nicholas W.; Chen, Sidi; Vibranovski, Maria D. (2013-11-23). "New Gene Evolution: Little Did We Know". Annual Review of Genetics (Annual Reviews) 47 (1): 307–333. doi:10.1146/annurev-genet-111212-133301. ISSN 0066-4197. PMID 24050177.
- ↑ 3.0 3.1 3.2 Ding, Yun; Zhou, Qi; Wang, Wen (2012-12-01). "Origins of New Genes and Evolution of Their Novel Functions". Annual Review of Ecology, Evolution, and Systematics (Annual Reviews) 43 (1): 345–363. doi:10.1146/annurev-ecolsys-110411-160513. ISSN 1543-592X.
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