Biology:TSPAN2

From HandWiki
A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Tetraspanin-2 is a protein that in humans is encoded by the TSPAN2 gene.[1][2][3]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[3]

References

  1. "Sequences and expression of six new members of the tetraspanin/TM4SF family". Biochim Biophys Acta 1399 (1): 101–4. Sep 1998. doi:10.1016/s0167-4781(98)00087-6. PMID 9714763. 
  2. Berditchevski F (Dec 2001). "Complexes of tetraspanins with integrins: more than meets the eye". J Cell Sci 114 (Pt 23): 4143–51. PMID 11739647. 
  3. 3.0 3.1 "Entrez Gene: TSPAN2 tetraspanin 2". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10100. 

Further reading

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