Biology:LY6G6E
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Short description: Pseudogene in the species Homo sapiens
 Generic protein structure example |
Lymphocyte antigen 6 complex, locus G6E (pseudogene) is a protein that in humans is encoded by the LY6G6E gene.[1]
Function
LY6G6E belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction.[2]
References
- ↑ "Entrez Gene: Lymphocyte antigen 6 complex, locus G6E pseudogene)". https://www.ncbi.nlm.nih.gov/gene/79136.
- ↑ "Transcriptional analysis of a novel cluster of LY-6 family members in the human and mouse major histocompatibility complex: five genes with many splice forms". Genomics 80 (1): 113–23. July 2002. doi:10.1006/geno.2002.6794. PMID 12079290.
Further reading
- "Characterization of the five novel Ly-6 superfamily members encoded in the MHC, and detection of cells expressing their potential ligands". Protein Science 15 (10): 2244–56. October 2006. doi:10.1110/ps.062242606. PMID 17008713.
- "Genes encoding three new members of the leukocyte antigen 6 superfamily and a novel member of Ig superfamily, together with genes encoding the regulatory nuclear chloride ion channel protein (hRNCC) and an N omega-N omega-dimethylarginine dimethylaminohydrolase homologue, are found in a 30-kb segment of the MHC class III region". Journal of Immunology 163 (1): 278–87. July 1999. doi:10.4049/jimmunol.163.1.278. PMID 10384126.
- "Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci". Arthritis and Rheumatism 60 (1): 53–62. January 2009. doi:10.1002/art.24138. PMID 19116923.
- "Complete sequence and gene map of a human major histocompatibility complex. The MHC sequencing consortium". Nature 401 (6756): 921–3. October 1999. doi:10.1038/44853. PMID 10553908.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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