Biology:Helicobacter hepaticus
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Short description: Species of bacterium
| Helicobacter hepaticus | |
|---|---|
| Scientific classification | |
| Kingdom: | |
| Phylum: | |
| Class: | Epsilon Proteobacteria
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| Order: | |
| Family: | |
| Genus: | |
| Species: | H. hepaticus
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| Binomial name | |
| Helicobacter hepaticus Fox et al., 1994
| |
Helicobacter hepaticus is a bacterium in the Helicobacteraceae family, Campylobacterales order.[1]
It has a spiral shape and bipolar, single, sheathed flagellum, and was first isolated from the livers of mice with active, chronic hepatitis. The bacteria also colonized the cecal and colonic mucosae of mice. It elicits persistent hepatitis in mice. It has also been associated with colorectal cancer and other diseases.[2][3] Its genome has been sequenced and is 1,799,146 bases long with 1,875 coding sequences.[4]
References
- ↑ "Helicobacter hepaticus sp. nov., a microaerophilic bacterium isolated from livers and intestinal mucosal scrapings from mice". Journal of Clinical Microbiology 32 (5): 1238–45. May 1994. doi:10.1128/JCM.32.5.1238-1245.1994. PMID 8051250.
- ↑ Fox, J G; Ge, Z; Whary, M T; Erdman, S E; Horwitz, B H (2010). "Helicobacter hepaticus infection in mice: models for understanding lower bowel inflammation and cancer". Mucosal Immunology 4 (1): 22–30. doi:10.1038/mi.2010.61. ISSN 1933-0219. PMID 20944559. PMC 3939708. http://dspace.mit.edu/bitstream/1721.1/88710/1/Fox_Helicobacter%20hepaticus.pdf.
- ↑ "Identification of widespread Helicobacter hepaticus infection in feces in commercial mouse colonies by culture and PCR assay". Journal of Clinical Microbiology 33 (11): 2968–72. November 1995. doi:10.1128/JCM.33.11.2968-2972.1995. PMID 8576355.
- ↑ Suerbaum, Sebastian (2003). "The complete genome sequence of the carcinogenic bacterium Helicobacter hepaticus". PNAS 100 (13): 7901–7906. doi:10.1073/pnas.1332093100. PMID 12810954. Bibcode: 2003PNAS..100.7901S.
Further reading
- "Eradication of Helicobacter bilis and H. hepaticus from infected mice by using a medicated diet". Lab Animal 36 (5): 37–40. May 2007. doi:10.1038/laban0507-37. PMID 17450169.
- "Detection of Helicobacter hepaticus in human bile samples of patients with biliary disease". Helicobacter 14 (6): 545–51. December 2009. doi:10.1111/j.1523-5378.2009.00729.x. PMID 19889072.
- "Natural history of Helicobacter hepaticus infection in conventional A/J mice, with special reference to liver involvement". Infection and Immunity 71 (6): 3667–72. June 2003. doi:10.1128/iai.71.6.3667-3672.2003. PMID 12761159.
- "Evaluation of antibiotic therapies for eradication of Helicobacter hepaticus". Antimicrobial Agents and Chemotherapy 39 (6): 1292–4. June 1995. doi:10.1128/aac.39.6.1292. PMID 7574518.
External links
Wikidata ☰ Q1602479 entry
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