Biology:EcpR1 sRNA
From HandWiki
EcpR1 (elongated cell phenotype RNA1) is a trans-encoded small non-coding RNA in the plant-symbiotic Sinorhizobium meliloti, previously named SmelC291, SmrC10, or Sra33.[1][2][3] According to its overproduction phenotype it was renamed Elongated Cell Phenotype RNA1.[4] Induced by stress, EcpR1 negatively regulates cell cycle master regulatory genes dnaA and gcrA at post-transcriptional level by base pairing between its strongly conserved GC-rich loop and the target mRNAs. It is suggested that EcpR1 connects stress adaptation and cell cycle progression.[4]
See also
Further reading
- ↑ "A genome-wide survey of sRNAs in the symbiotic nitrogen-fixing alpha-proteobacterium Sinorhizobium meliloti". BMC Genomics 11: 245. April 2010. doi:10.1186/1471-2164-11-245. PMID 20398411.
- ↑ "Conservation and Occurrence of Trans-Encoded sRNAs in the Rhizobiales". Genes 2 (4): 925–956. November 2011. doi:10.3390/genes2040925. PMID 24710299.
- ↑ "Identification of differentially expressed small non-coding RNAs in the legume endosymbiont Sinorhizobium meliloti by comparative genomics". Molecular Microbiology 66 (5): 1080–1091. December 2007. doi:10.1111/j.1365-2958.2007.05978.x. PMID 17971083.
- ↑ 4.0 4.1 "A stress-induced small RNA modulates alpha-rhizobial cell cycle progression". PLOS Genetics 11 (4): e1005153. April 2015. doi:10.1371/journal.pgen.1005153. PMID 25923724.
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