Biology:Citrobacter

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Short description: Genus of bacteria

Citrobacter
"Citrobacter freundii"
Citrobacter freundii
Scientific classification e
Domain: Bacteria
Phylum: Pseudomonadota
Class: Gammaproteobacteria
Order: Enterobacterales
Family: Enterobacteriaceae
Genus: Citrobacter
Werkman and Gillen, 1932
Species

Citrobacter is a genus of Gram-negative, aerobic, rod-shaped[2] coliform bacteria of the Enterobacteriaceae family.

Citrobacter spp. cause opportunistic infections (including urinary tract infections, gastroenteritis, and bacteremia).[2]

Microbiology

Microbial biochemistry

The species C. amalonaticus, C. koseri, and C. freundii can use citrate as a sole carbon source. Citrobacter species are differentiated by their ability to convert tryptophan to indole (C. koseri is the only citrobacter to be commonly indole-positive), ferment lactose (C. koseri is a lactose fermentor), and use malonate.[3]

Citrobacter shows the ability to accumulate uranium by building phosphate complexes.[4]

Environmental microbiology

These bacteria can be found almost everywhere in soil, water, wastewater, etc. They can also be found in the human intestine.[5][6]

Clinical significance

Citrobacter spp. are rarely the source of illnesses, except for infections of the GI tract, urinary tract and infant meningitis and sepsis.[clarification needed][5][6]

Antimicrobial resistance

Citrobacter freundii strains have inducible ampC genes encoding resistance to ampicillin and first-generation cephalosporins. In addition, isolates of Citrobacter may be resistant to many other antibiotics as a result of plasmid-encoded resistance genes.[citation needed]

References

  1. 1.0 1.1 1.2 Parte, A.C.. "Citrobacter". https://lpsn.dsmz.de/genus/citrobacter. 
  2. 2.0 2.1 "Dictionnaire médical de l'Académie de Médecine". https://www.academie-medecine.fr/le-dictionnaire/index.php?q=citrobacter. 
  3. Benjamin A. Lipsky; Edward W. Hook III; Arlene A. Smith; James J. Plorde (1980). "Citrobacter Infections in Humans: Experience at the Seattle Veterans Administration Medical Center and a Review of the Literature". Clin Infect Dis 2 (5): 746–760. doi:10.1093/clinids/2.5.746. ISSN 1058-4838. PMID 6763304. 
  4. L. E. Macaskie; R. M. Empson; A. K. Cheetham; C. P. Grey; A. J. Skarnulis (1992). "Uranium bioaccumulation by a Citrobacter sp. as a result of enzymically mediated growth of polycrystalline HUO2PO4". Science 257 (5071): 782–784. doi:10.1126/science.1496397. PMID 1496397. Bibcode1992Sci...257..782M. 
  5. 5.0 5.1 V. Drelichman; J. D. Band (1985). "Bacteremias due to Citrobacter diversus and Citrobacter freundii. Incidence, risk factors, and clinical outcome". Archives of Internal Medicine 145 (10): 1808–1810. doi:10.1001/archinte.145.10.1808. PMID 3899035. 
  6. 6.0 6.1 Badger, J.D.; M.F. Stins; K.S. Kim (1999). "Citrobacter freundii Invades and Replicates in Human Brain Microvascular Endothelial Cells". Infection and Immunity 67 (8): 4208–15. PMID 10417193. 

External links

Wikidata ☰ Q134081 entry