Biology:Chlorophenoxy herbicide

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Chlorophenoxy herbicides are a subclass of phenoxy herbicides which includes: MCPA, 2,4-D, 2,4,5-T and mecoprop.[1] Large amounts have been produced since the 1950s for agriculture.[2] Acute toxic effects after oral consumption are varied and may include: vomiting, abdominal pain, diarrhoea, gastrointestinal haemorrhage acutely followed by coma, hypertonia, hyperreflexia, ataxia, nystagmus, miosis, hallucinations and convulsions.[3] Treatment with urinary alkalinization may be helpful but evidence to support this practice is limited.[1][3]

See also

References

  1. 1.0 1.1 "Urinary alkalinisation for acute chlorophenoxy herbicide poisoning". Cochrane Database Syst Rev (1): CD005488. 2007. doi:10.1002/14651858.CD005488.pub2. PMID 17253558. 
  2. "Occupational Exposures to Chlorophenoxy Herbicides (IARC Summary & Evaluation, Volume 41, 1986)". http://www.inchem.org/documents/iarc/vol41/chlorophenoxyherbicides.html. 
  3. 3.0 3.1 "Poisoning due to chlorophenoxy herbicides". Toxicol Rev 23 (2): 65–73. 2004. doi:10.2165/00139709-200423020-00001. PMID 15578861.