Biology:CNTRL
From HandWiki
Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Centriolin is a protein that in humans is encoded by the CNTRL gene. It was previously known as CEP110.[1][2]
This gene encodes a centrosomal protein required for the centrosome to function as a microtubule organizing center. The gene product is also associated with centrosome maturation. One version of stem cell myeloproliferative disorder is the result of a reciprocal translocation between chromosomes 8 and 9, with the breakpoint associated with fibroblast growth factor receptor 1 and centriolin.[2]
References
- ↑ "FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)". Blood 95 (5): 1788–96. Mar 2000. doi:10.1182/blood.V95.5.1788.005k15_1788_1796. PMID 10688839.
- ↑ 2.0 2.1 "Entrez Gene: CEP110 centrosomal protein 110kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=11064.
External links
- Human CNTRL genome location and CNTRL gene details page in the UCSC Genome Browser.
Further reading
- "Centriolin anchoring of exocyst and SNARE complexes at the midbody is required for secretory-vesicle-mediated abscission.". Cell 123 (1): 75–87. 2005. doi:10.1016/j.cell.2005.07.027. PMID 16213214.
- "Humoral detection of leukaemia-associated antigens in presentation acute myeloid leukaemia.". Biochem. Biophys. Res. Commun. 335 (4): 1293–304. 2005. doi:10.1016/j.bbrc.2005.08.024. PMID 16112646.
- "Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly.". J. Cell Biol. 166 (5): 637–43. 2004. doi:10.1083/jcb.200405023. PMID 15337773.
- "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. 2004. doi:10.1038/ng1285. PMID 14702039.
- "A novel human protein of the maternal centriole is required for the final stages of cytokinesis and entry into S phase.". J. Cell Biol. 161 (3): 535–45. 2003. doi:10.1083/jcb.200301105. PMID 12732615.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "CEP110 and ninein are located in a specific domain of the centrosome associated with centrosome maturation.". J. Cell Sci. 115 (Pt 9): 1825–35. 2002. doi:10.1242/jcs.115.9.1825. PMID 11956314.
- "Assignment of the centrosomal protein 110 gene (Cep110) to mouse chromosome bands 2B-C1 by in situ hybridization.". Cytogenet. Cell Genet. 89 (3–4): 216–7. 2000. doi:10.1159/000015616. PMID 10965126.
- "Identification of a novel Sry-related gene and its germ cell-specific expression". Nucleic Acids Res. 27 (12): 2503–10. 1999. doi:10.1093/nar/27.12.2503. PMID 10359848.
- "Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling". J. Biol. Chem. 274 (15): 10203–12. 1999. doi:10.1074/jbc.274.15.10203. PMID 10187805.
- "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. 1997. doi:10.1101/gr.6.9.791. PMID 8889548.
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