Biology:CEP55

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Centrosomal protein of 55 kDa (Cep55), is a protein that in humans is encoded by the CEP55 gene.[1][2]

Cep55 is a mitotic phosphoprotein that plays a key role in cytokinesis, the final stage of cell division.[3] and cilia formation in neural stem cells.[4]

References

  1. "Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis". Dev Cell 9 (4): 477–88. Oct 2005. doi:10.1016/j.devcel.2005.09.003. PMID 16198290. 
  2. "Entrez Gene: CEP55 centrosomal protein 55kDa". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=55165. 
  3. "Cep55 stabilization is required for normal execution of cytokinesis". Cell Cycle 8 (22): 3742–3749. November 2009. doi:10.4161/cc.8.22.10047. PMID 19855176. 
  4. Behnam Rashidieh; Belal Shohayeb; Amanda Louise Bain; Patrick R. J. Fortuna; Debottam Sinha; Andrew Burgess; Richard Mills; Rachael C. Adams et al. (October 2021). "Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis". PLOS Genetics 17 (10): e1009334. doi:10.1371/journal.pgen.1009334. PMID 34710087. 

External links

Further reading