Biology:Belapectin

From HandWiki
Belapectin
Clinical data
Other names
  • GR-MD-02
  • Galactoarabino-rhamnogalacturonate
Legal status
Legal status
  • Investigational
Identifiers
CAS Number
UNII

Belapectin (also known as GR-MD-02) is a galectin-3 inhibitor developed by Galectin Therapeutics that is in clinical trials for the treatment of non-alcoholic steatohepatitis.[1][2][3][4]

References

  1. Mireku, Akosua (26 June 2023). "NASH drugs race to cross the finish line". https://www.pharmaceutical-technology.com/features/nash-drugs-race-to-cross-the-finish-line/?cf-view. 
  2. Al Attar, Atef; Antaramian, Ani; Noureddin, Mazen (3 April 2021). "Review of galectin-3 inhibitors in the treatment of nonalcoholic steatohepatitis". Expert Review of Clinical Pharmacology 14 (4): 457–464. doi:10.1080/17512433.2021.1894127. 
  3. Slack, R.J.; Mills, R.; Mackinnon, A.C. (January 2021). "The therapeutic potential of galectin-3 inhibition in fibrotic disease". The International Journal of Biochemistry & Cell Biology 130: 105881. doi:10.1016/j.biocel.2020.105881. 
  4. Tapper, Elliot B.; Ufere, Nneka N.; Huang, Daniel Q.; Loomba, Rohit (May 2022). "Review article: current and emerging therapies for the management of cirrhosis and its complications" (in en). Alimentary Pharmacology & Therapeutics 55 (9): 1099–1115. doi:10.1111/apt.16831. ISSN 0269-2813. https://doi.org/10.1111/apt.16831.