Biology:ACYP1

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Short description: Protein-coding gene in the species Homo sapiens


A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Acylphosphatase-1 is an enzyme that in humans is encoded by the ACYP1 gene.[1][2][3]

Function

Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis.[3]

References

  1. "Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase". FEBS Letters 367 (2): 145–8. Jun 1995. doi:10.1016/0014-5793(95)00553-L. PMID 7796909. 
  2. "Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3". Cytogenetics and Cell Genetics 81 (3–4): 235–6. Oct 1998. doi:10.1159/000015037. PMID 9730610. 
  3. 3.0 3.1 "Entrez Gene: ACYP1 acylphosphatase 1, erythrocyte (common) type". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=97. 

External links

Further reading