Biology:AAMDC

From HandWiki

The AAMDC gene encodes an AMDC or Adipogenesis Associated Mth938 Domain Containing protein that is integral to various cellular processes. The protein is involved in lipid metabolism, specifically adipogenesis, and plays a role in signal transduction as an oncoprotein.[1] The AAMDC protein is found in both the cytoplasmic and nuclear compartments of the cell.[2]

References

  1. Xiao, Rong; Li, Chengping; Wang, Chao; Cao, Yang; Zhang, Lichun; Guo, Yan; Xin, Youzhi; Zhang, Haiyan et al. (July 2019). "Adipogenesis associated Mth938 domain containing (AAMDC) protein expression is regulated by alternative polyadenylation and microRNAs". FEBS Letters 593 (14): 1724–1734. doi:10.1002/1873-3468.13449. ISSN 1873-3468. PMID 31116411. 
  2. Golden, Emily; Rashwan, Rabab; Woodward, Eleanor A.; Sgro, Agustin; Wang, Edina; Sorolla, Anabel; Waryah, Charlene; Tie, Wan Jun et al. (2021-03-26). "The oncogene AAMDC links PI3K-AKT-mTOR signaling with metabolic reprograming in estrogen receptor-positive breast cancer" (in en). Nature Communications 12 (1): 1920. doi:10.1038/s41467-021-22101-7. ISSN 2041-1723. PMID 33772001. Bibcode2021NatCo..12.1920G.