Biography:Christophe Dessimoz

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Christophe Dessimoz
Christophe Dessimoz ISMBECCB19-108 (48722254541).jpg
Christophe Dessimoz speaking at the Intelligent Systems for Molecular Biology (ISMB) / European Conference on Computational Biology (ECCB) in Basel, 2019
Born
Christophe Dessimoz

1980 (age 43–44)
Alma materETH Zurich (MSc, PhD)
Known forOrthologous MAtrix (OMA)[1]
AwardsOverton Prize (2019)[2]
Scientific career
FieldsBioinformatics
Genomics
Phylogenetics
Evolution
Computational Biology[3]
InstitutionsUniversity of Lausanne
European Bioinformatics Institute
University College London
Swiss Institute of Bioinformatics
ThesisComparative Genomics Using Pairwise Evolutionary Distances (2009)
Doctoral advisorGaston Gonnet[4]
Websitelab.dessimoz.org/people/christophe-dessimoz

Christophe Dessimoz is a Swiss National Science Foundation (SNSF) Professor at the University of Lausanne, Associate Professor at University College London and a group leader at the Swiss Institute of Bioinformatics.[5][3][6][7][8] He was awarded the Overton Prize in 2019 for his contributions to computational biology.[2]


Education

Dessimoz obtained his Master of Science degree in 2003[5] and PhD in Computer Science in 2009 from ETH Zurich in Switzerland [9] where his doctoral research was supervised by Gaston Gonnet[4] and examined by Amos Bairoch.[9]

Career and research

After postdoctoral research at the European Bioinformatics Institute (EBI) on the Wellcome Genome Campus in Hinxton, Cambridgeshire,[10] he joined University College London (UCL) as lecturer in 2013, and was promoted to Reader in 2015.[5] In 2015, he joined the University of Lausanne as professor, retaining an appointment at UCL.[11] Since 2016, Dessimoz has served as group leader at the Swiss Institute of Bioinformatics[5] where his research interests are in bioinformatics, genomics, phylogenetics, evolution and computational biology.[3][12][13][14][15]

Dessimoz is known for his management of the Orthologous MAtrix (OMA)[1] which provides information on orthologous proteins. OMA has important applications in protein function prediction.[2] Dessimoz's approach to benchmarking had a major impact on three key subfields of computational biology: orthology inference, sequence alignment, and the gene ontology (GO).[2][16][17]

Awards and honours

Dessimoz was awarded the Overton Prize by the International Society for Computational Biology (ISCB) in 2019 for outstanding contributions to computational biology.[2]

References

  1. 1.0 1.1 Altenhoff, Adrian M; Glover, Natasha M; Train, Clément-Marie; Kaleb, Klara; Warwick Vesztrocy, Alex; Dylus, David; de Farias, Tarcisio M; Zile, Karina et al. (2018). "The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces". Nucleic Acids Research 46 (D1): D477–D485. doi:10.1093/nar/gkx1019. ISSN 0305-1048. PMID 29106550. 
  2. 2.0 2.1 2.2 2.3 2.4 Kovats, Diane; Shamir, Ron; Fogg, Christiana (2019). "2019 ISCB Overton Prize: Christophe Dessimoz". F1000Research 8: 722. doi:10.12688/f1000research.19220.1. ISSN 2046-1402. PMID 31164977. 
  3. 3.0 3.1 3.2 {{Google Scholar id}} template missing ID and not present in Wikidata.
  4. 4.0 4.1 Christophe Dessimoz at the Mathematics Genealogy Project
  5. 5.0 5.1 5.2 5.3 Dessimoz, Christophe (2019). "Dessimoz Lab". https://lab.dessimoz.org/people/christophe-dessimoz. 
  6. Christophe Dessimoz publications from Europe PubMed Central
  7. Christophe Dessimoz publications indexed by the Scopus bibliographic database. (Subscription content?)
  8. {{Twitter}} template missing ID and not present in Wikidata.
  9. 9.0 9.1 Dessimoz, Christophe (2009). Comparative Genomics Using Pairwise Evolutionary Distances. ethz.ch (PhD thesis). ETH Zurich. doi:10.3929/ethz-a-005762050. OCLC 935351416. open access
  10. Goldman, Nick; Bertone, Paul; Chen, Siyuan; Dessimoz, Christophe; LeProust, Emily M.; Sipos, Botond; Birney, Ewan (2013). "Towards practical, high-capacity, low-maintenance information storage in synthesized DNA". Nature 494 (7435): 77–80. doi:10.1038/nature11875. ISSN 0028-0836. PMID 23354052. Bibcode2013Natur.494...77G. 
  11. "Dr Christophe Dessimoz". https://www.ucl.ac.uk/biosciences/departments/gee/staff/tabs/academic-iris-link/dessimoz. Retrieved 6 March 2019. 
  12. Wodak, Shoshana; Sunnåker, Mikael; Busetto, Alberto Giovanni; Numminen, Elina; Corander, Jukka; Foll, Matthieu; Dessimoz, Christophe (2013). "Approximate Bayesian Computation". PLoS Computational Biology 9 (1): e1002803. doi:10.1371/journal.pcbi.1002803. ISSN 1553-7358. PMID 23341757. Bibcode2013PLSCB...9E2803S. 
  13. Anisimova, Maria; Gil, Manuel; Dufayard, Jean-François; Dessimoz, Christophe; Gascuel, Olivier (2011). "Survey of Branch Support Methods Demonstrates Accuracy, Power, and Robustness of Fast Likelihood-based Approximation Schemes". Systematic Biology 60 (5): 685–699. doi:10.1093/sysbio/syr041. ISSN 1076-836X. PMID 21540409. 
  14. Eisen, Jonathan A.; Altenhoff, Adrian M.; Dessimoz, Christophe (2009). "Phylogenetic and Functional Assessment of Orthologs Inference Projects and Methods". PLoS Computational Biology 5 (1): e1000262. doi:10.1371/journal.pcbi.1000262. ISSN 1553-7358. PMID 19148271. Bibcode2009PLSCB...5E0262A. 
  15. Abbosh, Christopher; Birkbak, Nicolai J.; Wilson, Gareth A.; Jamal-Hanjani, Mariam; Constantin, Tudor; Salari, Raheleh; Le Quesne, John; Moore, David A. et al. (2017). "Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution". Nature 545 (7655): 446–451. doi:10.1038/nature22364. ISSN 0028-0836. PMID 28445469. Bibcode2017Natur.545..446A. 
  16. Dessimoz, Christophe (2017). The Gene Ontology Handbook. Methods in Molecular Biology. 1446. doi:10.1007/978-1-4939-3743-1. ISBN 9781493937431.  open access
  17. Gaudet, Pascale; Škunca, Nives; Hu, James C.; Dessimoz, Christophe (2017). "Primer on the Gene Ontology". The Gene Ontology Handbook. Methods in Molecular Biology. 1446. pp. 25–37. doi:10.1007/978-1-4939-3743-1_3. ISBN 978-1-4939-3741-7.